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Jan D Bos Selected Research

monobenzone (Benoquin)

6/2011Skin-depigmenting agent monobenzone induces potent T-cell autoimmunity toward pigmented cells by tyrosinase haptenation and melanosome autophagy.
5/2010Effective melanoma immunotherapy in mice by the skin-depigmenting agent monobenzone and the adjuvants imiquimod and CpG.

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Jan D Bos Research Topics

Disease

21Psoriasis (Pustulosis Palmaris et Plantaris)
09/2012 - 11/2002
11Atopic Dermatitis (Atopic Eczema)
01/2018 - 01/2002
6Inflammation (Inflammations)
01/2018 - 10/2002
4Psoriatic Arthritis
09/2012 - 10/2002
3Hyperpigmentation
10/2012 - 09/2010
3Pruritus (Itching)
06/2012 - 02/2006
3Melanoma (Melanoma, Malignant)
09/2011 - 05/2010
3Infections
11/2008 - 07/2002
2Eczema
03/2014 - 07/2002
2Erythema
10/2012 - 03/2011
2Skin Diseases (Skin Disease)
03/2012 - 01/2002
2Neoplasms (Cancer)
09/2011 - 05/2010
2Melanosis (Freckles)
03/2011 - 09/2010
2Hypersensitivity (Allergy)
08/2008 - 02/2006
1Autoimmune Thyroiditis (Lymphomatous Thyroiditis)
01/2013
1Fibrosis (Cirrhosis)
03/2012
1Nevus (Nevi)
12/2011
1Vitiligo
06/2011
1Edema (Dropsy)
03/2011
1Pain (Aches)
03/2011
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
10/2010
1Cutaneous Lupus Erythematosus
10/2010
1Allergic Contact Dermatitis
01/2009
1Hypopigmentation (Hypomelanosis)
11/2006
1Neurogenic Inflammation
02/2006
1Fatigue
01/2006
1Sunburn
01/2005
1Contact Dermatitis (Eczema, Contact)
07/2004
1Necrosis
01/2004

Drug/Important Bio-Agent (IBA)

7CytokinesIBA
09/2012 - 01/2002
5Proteins (Proteins, Gene)FDA Link
09/2012 - 04/2002
4Melanins (Melanin)IBA
10/2012 - 01/2005
4AntigensIBA
09/2012 - 05/2010
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2010 - 04/2002
3Filaggrin ProteinsIBA
03/2014 - 04/2010
3Alefacept (Amevive)FDA Link
09/2012 - 10/2002
3Etanercept (Enbrel)FDA Link
08/2010 - 01/2006
3pimecrolimus (Elidel)FDA Link
01/2007 - 01/2002
3Methotrexate (Mexate)FDA LinkGeneric
06/2004 - 08/2003
2AllergensIBA
01/2018 - 03/2008
2Adalimumab (Humira)FDA Link
01/2012 - 02/2010
2Monophenol Monooxygenase (Tyrosinase)IBA
09/2011 - 06/2011
2Differentiation AntigensIBA
09/2011 - 06/2011
2monobenzone (Benoquin)FDA Link
06/2011 - 05/2010
2Therapeutic UsesIBA
05/2010 - 04/2003
2Infliximab (Remicade)FDA Link
08/2008 - 01/2004
2Complement System Proteins (Complement)IBA
04/2007 - 02/2006
2Cyclosporine (Ciclosporin)FDA LinkGeneric
06/2004 - 08/2003
2Biological ProductsIBA
01/2004 - 11/2002
2Interleukin-4 (Interleukin 4)IBA
01/2003 - 04/2002
1Thyroid HormonesIBA
01/2013
1interleukin 20 (IL-20)IBA
09/2012
1InterleukinsIBA
06/2012
1Biomarkers (Surrogate Marker)IBA
01/2012
1Dihydrotachysterol (AT 10)IBA
12/2011
1Peptides (Polypeptides)IBA
09/2011
1HLA-A2 Antigen (HLA A2 Antigen)IBA
09/2011
1quinone (benzoquinone)IBA
06/2011
1HaptensIBA
06/2011
1hydroquinone (Esoterica)FDA Link
03/2011
1Tretinoin (Retinoic Acid)FDA LinkGeneric
03/2011
1Triamcinolone Acetonide (Azmacort)FDA LinkGeneric
03/2011
1Interleukin-22 (IL-22)IBA
11/2010
1Interleukin-17 (Interleukin 17)IBA
11/2010
1N-phthaloylglutamic acidIBA
09/2010
1Prostaglandins AIBA
09/2010
1Pancreatic Elastase (Elastase)IBA
08/2010
1Skin Lightening PreparationsIBA
05/2010
1Imiquimod (Aldara)FDA LinkGeneric
05/2010
1AntibodiesIBA
02/2010
1Interleukin-12 (IL 12)IBA
11/2008
1GlucocorticoidsIBA
09/2008
1Vitamin DFDA LinkGeneric
09/2008
1Toll-Like Receptors (Toll-Like Receptor)IBA
09/2008
1Immunoglobulin E (IgE)IBA
03/2008
1LigandsIBA
09/2007
1CCR5 Receptors (CCR5 Receptor)IBA
09/2007
1Chemokine ReceptorsIBA
09/2007
1Chemokine CCL5IBA
09/2007
1AncrivirocIBA
09/2007
1Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric
01/2007
1Clindamycin (Cleocin)FDA LinkGeneric
11/2006
1Benzoyl PeroxideFDA LinkGeneric
11/2006
1Fluticasone (Cutivate)FDA LinkGeneric
11/2006
1efalizumab (Raptiva)FDA Link
04/2006
1Interleukin-23 (Interleukin 23)IBA
02/2006
1E-SelectinIBA
08/2005
1Urocanic AcidIBA
07/2004
1Picryl Chloride (Trinitrochlorobenzene)IBA
07/2004
1Pharmaceutical PreparationsIBA
04/2004

Therapy/Procedure

14Therapeutics
01/2012 - 08/2003
5Laser Therapy (Surgery, Laser)
10/2012 - 09/2010
4Lasers (Laser)
10/2012 - 09/2010
3Immunotherapy
09/2011 - 05/2010
1Aftercare (After-Treatment)
09/2012
1Rejuvenation
03/2012
1Withholding Treatment
05/2010
1Ligation
07/2004
1Duration of Therapy
03/2004
1Remission Induction
03/2004